DETAILED NOTES ON BOSENTAN

Ketoconazole Coadministration of bosentan 125 mg twice each day and ketoconazole, a powerful CYP3A inhibitor, amplified the plasma concentrations of bosentan by somewhere around 100% in typical volunteers. No dose adjustment of bosentan is important, but enhanced outcomes of bosentan must be viewed as.Explain to your health practitioner When you've